Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Vegfa  vascular endothelial growth factor A   (Synonyms: Vegf, VEGF120, VEGF164, VEGF188, VEGF-A, VPF)
Results	Reference
1	J:303634 Arai Y, Ito M, Tanaka K, Ozawa J, Motojima Y, Matsuoka K, Igarashi K, Namba F, Increased expression of heme oxygenase-1 suppresses airway branching morphogenesis in fetal mouse lungs exposed to inflammation. Pediatr Res. 2020 Feb;87(3):494-500
1	J:119152 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89
1*	J:63357 Bhatt AJ, Amin SB, Chess PR, Watkins RH, Maniscalco WM, Expression of vascular endothelial growth factor and Flk-1 in developing and glucocorticoid-treated mouse lung. Pediatr Res. 2000 May;47(5):606-13
1	J:303643 Bi X, Wang K, Yang L, Pan H, Jiang H, Wei Q, Fang M, Yu H, Zhu C, Cai Y, He Y, Gan X, Zeng H, Yu D, Zhu Y, Jiang H, Qiu Q, Yang H, Zhang YE, Wang W, Zhu M, He S, Zhang G, Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes. Cell. 2021 Mar 4;184(5):1377-1391.e14
1	J:112223 Bissonauth V, Roy S, Gravel M, Guillemette S, Charron J, Requirement for Map2k1 (Mek1) in extra-embryonic ectoderm during placentogenesis. Development. 2006 Sep;133(17):3429-40
1*	J:27451 Breier G, Albrecht U, Sterrer S, Risau W, Expression of vascular endothelial growth factor during embryonic angiogenesis and endothelial cell differentiation. Development. 1992 Feb;114(2):521-32
1*	J:29513 Breier G, Clauss M, Risau W, Coordinate expression of vascular endothelial growth factor receptor-1 (flt-1) and its ligand suggests a paracrine regulation of murine vascular development. Dev Dyn. 1995 Nov;204(3):228-39
1*	J:29522 Chakraborty I, Das SK, Dey SK, Differential expression of vascular endothelial growth factor and its receptor mRNAs in the mouse uterus around the time of implantation. J Endocrinol. 1995 Nov;147(2):339-52
1*	J:25542 Dumont DJ, Fong GH, Puri MC, Gradwohl G, Alitalo K, Breitman ML, Vascularization of the mouse embryo: a study of flk-1, tek, tie, and vascular endothelial growth factor expression during development. Dev Dyn. 1995 May;203(1):80-92
1*	J:41526 Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y, A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1alpha regulates the VEGF expression and is potentially involved in lung and vascular development. Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4273-8
1	J:75861 Fukai N, Eklund L, Marneros AG, Oh SP, Keene DR, Tamarkin L, Niemela M, Ilves M, Li E, Pihlajaniemi T, Olsen BR, Lack of collagen XVIII/endostatin results in eye abnormalities. EMBO J. 2002 Apr 2;21(7):1535-44
1	J:199943 Golovchenko S, Hattori T, Hartmann C, Gebhardt M, Gebhard S, Hess A, Pausch F, Schlund B, von der Mark K, Deletion of beta catenin in hypertrophic growth plate chondrocytes impairs trabecular bone formation. Bone. 2013 Jul;55(1):102-12
1	J:76918 Greenberg JM, Thompson FY, Brooks SK, Shannon JM, McCormick-Shannon K, Cameron JE, Mallory BP, Akeson AL, Mesenchymal expression of vascular endothelial growth factors D and A defines vascular patterning in developing lung. Dev Dyn. 2002 Jun;224(2):144-53
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:63336 Halder JB, Zhao X, Soker S, Paria BC, Klagsbrun M, Das SK, Dey SK, Differential expression of VEGF isoforms and VEGF(164)-specific receptor neuropilin-1 in the mouse uterus suggests a role for VEGF(164) in vascular permeability and angiogenesis during implantation. Genesis. 2000 Mar;26(3):213-24
1	J:159025 Hattori T, Muller C, Gebhard S, Bauer E, Pausch F, Schlund B, Bosl MR, Hess A, Surmann-Schmitt C, von der Mark H, de Crombrugghe B, von der Mark K, SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development. 2010 Mar;137(6):901-11
1	J:68468 Huss WJ, Hanrahan CF, Barrios RJ, Simons JW, Greenberg NM, Angiogenesis and prostate cancer: identification of a molecular progression switch. Cancer Res. 2001 Mar 15;61(6):2736-43
1	J:215739 Kazanskaya O, Ohkawara B, Heroult M, Wu W, Maltry N, Augustin HG, Niehrs C, The Wnt signaling regulator R-spondin 3 promotes angioblast and vascular development. Development. 2008 Nov;135(22):3655-64
1	J:320427 Kobayashi H, Liu J, Urrutia AA, Burmakin M, Ishii K, Rajan M, Davidoff O, Saifudeen Z, Haase VH, Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development. Kidney Int. 2017 Dec;92(6):1370-1383
1	J:137720 Kubota Y, Hirashima M, Kishi K, Stewart CL, Suda T, Leukemia inhibitory factor regulates microvessel density by modulating oxygen-dependent VEGF expression in mice. J Clin Invest. 2008 Jul;118(7):2393-403
1	J:160163 Kurihara T, Kubota Y, Ozawa Y, Takubo K, Noda K, Simon MC, Johnson RS, Suematsu M, Tsubota K, Ishida S, Goda N, Suda T, Okano H, von Hippel-Lindau protein regulates transition from the fetal to the adult circulatory system in retina. Development. 2010 May;137(9):1563-71
1	J:48459 Lagercrantz J, Farnebo F, Larsson C, Tvrdik T, Weber G, Piehl F, A comparative study of the expression patterns for vegf, vegf-b/vrf and vegf-c in the developing and adult mouse. Biochim Biophys Acta. 1998 Jun 16;1398(2):157-63
1	J:202964 Lai LP, Lilley BN, Sanes JR, McMahon AP, Lkb1/Stk11 regulation of mTOR signaling controls the transition of chondrocyte fates and suppresses skeletal tumor formation. Proc Natl Acad Sci U S A. 2013 Nov 26;110(48):19450-5
1	J:291947 Luck R, Urban S, Karakatsani A, Harde E, Sambandan S, Nicholson L, Haverkamp S, Mann R, Martin-Villalba A, Schuman EM, Acker-Palmer A, Ruiz de Almodovar C, VEGF/VEGFR2 signaling regulates hippocampal axon branching during development. Elife. 2019 Dec 23;8:e49818
1	J:320175 Maeda Y, Miwa Y, Sato I, Expression of CGRP, vasculogenesis and osteogenesis associated mRNAs in the developing mouse mandible and tibia. Eur J Histochem. 2017 Jan 23;61(1):2750
1	J:87618 Maes C, Stockmans I, Moermans K, Van Looveren R, Smets N, Carmeliet P, Bouillon R, Carmeliet G, Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival. J Clin Invest. 2004 Jan;113(2):188-99
1	J:153980 Matsushita T, Chan YY, Kawanami A, Balmes G, Landreth GE, Murakami S, Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. Mol Cell Biol. 2009 Nov;29(21):5843-57
1	J:141347 Muthig V, Gilsbach R, Haubold M, Philipp M, Ivacevic T, Gessler M, Hein L, Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenoceptor deficient mice. Circ Res. 2007 Sep 28;101(7):682-91
1	J:120969 Pollard PJ, Spencer-Dene B, Shukla D, Howarth K, Nye E, El-Bahrawy M, Deheragoda M, Joannou M, McDonald S, Martin A, Igarashi P, Varsani-Brown S, Rosewell I, Poulsom R, Maxwell P, Stamp GW, Tomlinson IP, Targeted inactivation of fh1 causes proliferative renal cyst development and activation of the hypoxia pathway. Cancer Cell. 2007 Apr;11(4):311-9
1*	J:145030 Raffel GD, Chu GC, Jesneck JL, Cullen DE, Bronson RT, Bernard OA, Gilliland DG, Ott1 (Rbm15) is essential for placental vascular branching morphogenesis and embryonic development of the heart and spleen. Mol Cell Biol. 2009 Jan;29(2):333-41
1	J:201133 Rattner A, Yu H, Williams J, Smallwood PM, Nathans J, Endothelin-2 signaling in the neural retina promotes the endothelial tip cell state and inhibits angiogenesis. Proc Natl Acad Sci U S A. 2013 Oct 1;110(40):E3830-E3839
1	J:61911 Reese J, Binart N, Brown N, Ma WG, Paria BC, Das SK, Kelly PA, Dey SK, Implantation and decidualization defects in prolactin receptor (PRLR)-deficient mice are mediated by ovarian but not uterine PRLR. Endocrinology. 2000 May;141(5):1872-81
1	J:314585 Shadad O, Chaulagain R, Luukko K, Kettunen P, Establishment of tooth blood supply and innervation is developmentally regulated and takes place through differential patterning processes. J Anat. 2019 Apr;234(4):465-479
1*	J:4758 Shweiki D, Itin A, Neufeld G, Gitay-Goren H, Keshet E, Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis. J Clin Invest. 1993 May;91(5):2235-43
1	J:240973 Tao C, Zhang X, Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis. Cell Rep. 2016 Nov 08;17(7):1832-1844
1*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:149923 Ueda H, Miyazaki Y, Matsusaka T, Utsunomiya Y, Kawamura T, Hosoya T, Ichikawa I, Bmp in podocytes is essential for normal glomerular capillary formation. J Am Soc Nephrol. 2008 Apr;19(4):685-94
1	J:297253 Vila Ellis L, Cain MP, Hutchison V, Flodby P, Crandall ED, Borok Z, Zhou B, Ostrin EJ, Wythe JD, Chen J, Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. 2020 Mar 9;52(5):617-630.e6
1	J:128959 Wang H, Xie H, Sun X, Tranguch S, Zhang H, Jia X, Wang D, Das SK, Desvergne B, Wahli W, Dubois RN, Dey SK, Stage-specific Integration of Maternal and Embryonic Peroxisome Proliferator-activated Receptor {delta} Signaling Is Critical to Pregnancy Success. J Biol Chem. 2007 Dec 28;282(52):37770-37782
1	J:35566 Yang K, Cepko CL, Flk-1, a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells. J Neurosci. 1996 Oct 1;16(19):6089-99
1	J:70892 Ylikorkala A, Rossi DJ, Korsisaari N, Luukko K, Alitalo K, Henkemeyer M, Makela TP, Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice. Science. 2001 Aug 17;293(5533):1323-6
1	J:310317 Zhang S, Kong S, Wang B, Cheng X, Chen Y, Wu W, Wang Q, Shi J, Zhang Y, Wang S, Lu J, Lydon JP, DeMayo F, Pear WS, Han H, Lin H, Li L, Wang H, Wang YL, Li B, Chen Q, Duan E, Wang H, Uterine Rbpj is required for embryonic-uterine orientation and decidual remodeling via Notch pathway-independent and -dependent mechanisms. Cell Res. 2014 Aug;24(8):925-42
1	J:238902 Zhou G, Jiang X, Zhang H, Lu Y, Liu A, Ma X, Yang G, Yang R, Shen H, Zheng J, Hu Y, Yang X, Zhang WJ, Xie Z, Zbtb20 regulates the terminal differentiation of hypertrophic chondrocytes via repression of Sox9. Development. 2015 Jan 15;142(2):385-93